Abstract
IN your issue of December 23 (p. 171) appears a letter from Dr. E. Klein, in which that gentleman attempts to show that the micro-organisms found by Dr. Graham Brown, Mr. Sherrington, and myself in the substance of the mucous membrane of the small intestine in cases of Cholera asiatica are nothing more than “common mould (probably aspergillus),” which has grown on and into the tissue during the process of hardening. We were and are, however, perfectly well acquainted with the fact that imperfectly preserved animal tissues are liable to be invaded by various forms of fungi, and took, therefore, precautions which we believe to be ample to prevent such contamination of our material. Moreover, the presence of the micro-organisms in certain parts of the tissues only, their absence in others or on the surface of the specimens, the fact that their presence in the part is accompanied by anatomical changes which could not have taken place during the process of hardening, and, most of all, the characters of the micro-organisms themselves, render such an hypothesis as that brought forward by Dr. Klein absolutely unacceptable.
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ROY, C. The Cambridge Cholera Fungus. Nature 35, 223 (1887). https://doi.org/10.1038/035223a0
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DOI: https://doi.org/10.1038/035223a0
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