Acta Pharmacologica Sinica

Structure genomics of SARS-CoV-2 and its Omicron variant

Targeted degradation of membrane and extracellular proteins with LYTACs

Yu-yang Li
Yang Yang
Song-bo Xie

Review Article 05 August 2024

Featured

The correlation between mitochondria-associated endoplasmic reticulum membranes (MAMs) and Ca²⁺ transport in the pathogenesis of diseases

Wen-bin Zhao
Rui Sheng
Review Article08 Aug 2024
Foxp3 inhibitory peptide encapsulated in a novel CD25-targeted nanoliposome promotes efficient tumor regression in mice

Alejandro Serrano
Noelia Casares
María J. Garrido
ArticleOpen Access29 Jul 2024
A small molecule compound targeting hemagglutinin inhibits influenza A virus and exhibits broad-spectrum antiviral activity

Yin-yan Li
Guo-dong Liang
Jie Yang
Article10 Jul 2024
Luteolin-7-diglucuronide, a novel PTP1B inhibitor, ameliorates hepatic stellate cell activation and liver fibrosis in mice

Bi-xi Tang
Yong Zhang
Yi Zang
Article05 Aug 2024

Current issue

Krüppel-like factors: potential roles in blood-brain barrier dysfunction and epileptogenesis

Ana Beatriz Santos
Andreia Carona
Joana Bicker
Review Article29 Apr 2024
Insomnia-related rodent models in drug discovery

Ze-ka Chen
Yuan-yuan Liu
Zhi-li Huang
Review Article26 Apr 2024
E3 ubiquitin ligase UBR5 modulates circadian rhythm by facilitating the ubiquitination and degradation of the key clock transcription factor BMAL1

Chun-yan Duan
Yue Li
Guoqiang Xu
Article13 May 2024
PHLDA1 contributes to hypoxic ischemic brain injury in neonatal rats via inhibiting FUNDC1-mediated mitophagy

Xiao-lu Jiang
Zu-bin Zhang
Mei Li
Article15 May 2024
Sodium oligomannate activates the enteroendocrine-vagal afferent pathways in APP/PS1 mice

Hua-shan Gong
Jing-pei Pan
Wei-fang Rong
Article03 May 2024
Thermoregulatory pathway underlying the pyrogenic effects of prostaglandin E₂ in the lateral parabrachial nucleus of male rats

Jian-hui Xu
Tian-hui He
Jie Zhang
Article03 May 2024

Volume 45 Issue 9

Contents

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Announcements

JOIN US | Deputy Director Position of SKLDR

State Key Laboratory of Drug Research (SKLDR), which was approved by Chinese Academy of Sciences under the unremitting efforts of reorganizing the state key laboratory system, is recruiting a Deputy Director. The candidate is expected to help SKLDR to continuously improve the academic influence and the ability to transform new drug achievements into real productivity.

Browse articles

SGLT2 inhibitors ameliorate NAFLD in mice via downregulating PFKFB3, suppressing glycolysis and modulating macrophage polarization

Xia-fang Lin
Xiao-na Cui
Tian-pei Hong
ArticleOpen Access18 Sept 2024
Bile duct ligation impairs visual acuity in rats by ammonia- and bilirubin-induced retinal degeneration

Yi-ting Yang
Ming-rui Ji
Li Liu
Article18 Sept 2024
G3BP2 promotes tumor progression and gemcitabine resistance in PDAC via regulating PDIA3-DKC1-hENT in a stress granules-dependent manner

Fa-liang Xing
Bo-rui Li
Bo Zhang
Article17 Sept 2024
Activation of D2-like dopamine receptors improves the neuronal network and cognitive function of PPT1KI mice

Jun-qiang Zhao
Bing-yan Feng
Cheng-biao Lu
Article16 Sept 2024
Baicalein ameliorates chronic itch in ACD mice by suppressing the spinal astrocytic STAT3–LCN2 cascade

Li-xia Du
Xin-yi Gao
Zhi-fei Wang
Article16 Sept 2024
Exploring the constitutive activation mechanism of the class A orphan GPR20

Ming-yang Zhang
Jian-yang Ao
Shao-yong Lu
Article10 Sept 2024
Cardiovascular adverse effects of antiviral therapies for COVID-19: Evidence and plausible mechanisms

Eileen Chen
Lei Xi
Review ArticleOpen Access09 Sept 2024
Artemisinin inhibits neuronal ferroptosis in Alzheimer’s disease models by targeting KEAP1

Peng-xi Deng
Marta Silva
Wen-hua Zheng
Article09 Sept 2024
Palmitoyltransferase ZDHHC3 is essential for the oncogenic activity of PML/RARα in acute promyelocytic leukemia

Xue-jing Shao
Wei Wang
Bo Yang
Article03 Sept 2024

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