Acta Pharmacologica Sinica

Structure genomics of SARS-CoV-2 and its Omicron variant: drug design templates for COVID-19

Can-rong Wu
Wan-chao Yin
H. Eric Xu

Review Article 20 January 2022

Featured

Bile acid and receptors: biology and drug discovery for nonalcoholic fatty liver disease

Ting-ying Jiao
Yuan-di Ma
Cen Xie
Review Article 25 Feb 2022
Mitochondria homeostasis: Biology and involvement in hepatic steatosis to NASH

Yu-feng Li
Zhi-fu Xie
Jing-ya Li
Review Article 01 Feb 2022
GLP-1 mimetics as a potential therapy for nonalcoholic steatohepatitis

Yan Chen
Ying-na Xu
Ming-wei Wang
Review Article 21 Dec 2021
Current status and challenges in the drug treatment for fibrotic nonalcoholic steatohepatitis

Yi-wen Shi
Jian-gao Fan
Review Article 14 Dec 2021

Current issue

Metabolic reprograming of MDSCs within tumor microenvironment and targeting for cancer immunotherapy

Qing Li
Ming Xiang
Review Article 24 Sept 2021
Iptakalim improves cerebral microcirculation in mice after ischemic stroke by inhibiting pericyte contraction

Ruo-bing Guo
Yin-feng Dong
Xiu-lan Sun
Article 25 Oct 2021
Metformin promotes microglial cells to facilitate myelin debris clearance and accelerate nerve repairment after spinal cord injury

Yan-qing Wu
Jun Xiong
Jian Xiao
Article 03 Sept 2021
Novel selective κ agonists SLL-039 and SLL-1206 produce potent antinociception with fewer sedation and aversion

Yuan-yuan Wei
Yan Ma
Jing-gen Liu
Article 07 Sept 2021
LncRNA-6395 promotes myocardial ischemia-reperfusion injury in mice through increasing p53 pathway

Lin-feng Zhan
Qi Zhang
Ming-yu Zhang
Article 07 Sept 2021
Asiatic acid alleviates ischemic myocardial injury in mice by modulating mitophagy- and glycophagy-based energy metabolism

Fan Qiu
Yi Yuan
Ling Gao
Article 14 Sept 2021

Volume 43 Issue 6

Contents

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Acta Pharmacologica Sinica is a Transformative Journal; authors can publish using the traditional publishing route OR via immediate gold Open Access.

Our Open Access option complies with funder and institutional requirements.

Browse articles

Hederacoside C ameliorates colitis via restoring impaired intestinal barrier through moderating S100A9/MAPK and neutrophil recruitment inactivation

Zheng-xia Zha
Yu Lin
Yan-li Liu
Article 22 Jun 2022
CP-25 enhances OAT1-mediated absorption of methotrexate in synoviocytes of collagen-induced arthritis rats

Chun Wang
Hao Tang
Wei Wei
Article 22 Jun 2022
Channelopathy of small- and intermediate-conductance Ca²⁺-activated K⁺ channels

Young-Woo Nam
Myles Downey
Miao Zhang
Review Article 17 Jun 2022
Costunolide alleviates atherosclerosis in high-fat diet-fed ApoE^−/− mice through covalently binding to IKKβ and inhibiting NF-κB-mediated inflammation

Zhu-qi Huang
Wu Luo
Guang Liang
Article 16 Jun 2022
Dual-responsive nanoparticles loading bevacizumab and gefitinib for molecular targeted therapy against non-small cell lung cancer

Zi-tong Zhao
Jue Wang
Ya-ping Li
Article 15 Jun 2022
Silybin regulates P450s activity by attenuating endoplasmic reticulum stress in mouse nonalcoholic fatty liver disease

Jing Wu
Yun-ge Lou
Yuan Xie
Article 15 Jun 2022
Dectin-1 plays a deleterious role in high fat diet-induced NAFLD of mice through enhancing macrophage activation

Min-xiu Wang
Wu Luo
Guang Liang
Article 10 Jun 2022
Calcipotriol abrogates cancer-associated fibroblast-derived IL-8-mediated oxaliplatin resistance in gastric cancer cells via blocking PI3K/Akt signaling

Zhen-xiong Zhao
Yan-qiu Zhang
Mi-die Xu
Article 08 Jun 2022
Pharmacokinetics, mass balance, and metabolism of [¹⁴C]TPN171, a novel PDE5 inhibitor, in humans for the treatment of pulmonary arterial hypertension

Yi-fei He
Yin Liu
Xing-xing Diao
Article 08 Jun 2022

Collections

40 years of APS

We celebrate the 40th anniversary of Acta Pharmacologica Sinica (APS) with a series of specially commissioned Reviews and Articles across the diverse areas of the journal’s scope, highlighting the advances made in pharmacological research.

Focus 04 Sept 2020

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EMBO Workshop: Molecular mechanisms in evolution and ecology

05 October 2022 – 08 October 2022

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EMBO Practical Course: The fundamentals of high-end cell sorting

30 October 2022 – 04 November 2022

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EMBO Practical Course: Synthetic biology in action: beyond standard metabolism

11 September 2022 – 18 September 2022

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09 February 2023 – 12 February 2023

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05 September 2022 – 08 September 2022

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