Mitochondria are intracellular organelles that contain a large set of proteins to help them produce energy, among other functions. A systematic analysis reveals how mitochondrial proteins are organized into complexes and assemblies, facilitating the identification of the molecular mechanisms and pathways that underlie the organelle’s many functions.

High-resolution structures of the bacterial Rho protein in complex with an RNA polymerase enzyme and partner proteins provide support for the long-held model of how Rho helps to terminate gene transcription.

The study of how chemical reactions work is key to the design of new reactions, but relies on hard work and expert knowledge. A machine-learning tool has been developed that could change the way this challenge is approached.

A new ultrasound patch can image the heart while being worn, even when the wearer is moving during strenuous exercise. A customized model that uses a technique of artificial intelligence called deep learning then processes the images to extract important measures of cardiac performance.