China’s coronavirus vaccines are leaping ahead – but face challenges as virus wanes

Companies could struggle to enrol enough trial participants, or gather enough data to convince regulatory agencies that the shots work.


  • Ocean heatwaves displace surface isotherms by tens to thousands of kilometres—comparable to shifts associated with long-term warming trends—potentially driving rapid redistributions of marine species.

    • Michael G. Jacox
    • Michael A. Alexander
    • James D. Scott
  • The approximately 5-Gb tuatara (Sphenodon punctatus) genome assembly provides a resource for analysing amniote evolution, and highlights the imperative for meaningful cultural engagement with Indigenous communities in genome-sequencing endeavours.

    • Neil J. Gemmell
    • Kim Rutherford
    • Haydn Edmonds
  • A colloidal system is used to demonstrate the Mpemba effect and obtain the parameters responsible for its anomalous relaxation dynamics, which are manipulated to achieve exponentially faster cooling than typical.

    • Avinash Kumar
    • John Bechhoefer
  • During the activation of mouse macrophages by lipopolysaccharides, histone deacetylase 3 controls inflammatory responses by both repressing and activating gene transcription depending on its differential association with transcription factors.

    • Hoang C. B. Nguyen
    • Marine Adlanmerini
    • Mitchell A. Lazar
Cystic fibrosis

Cystic fibrosis

New therapies are turning cystic fibrosis, an inherited disorder that causes a vicious cycle of mucus build-up, infection and inflammation, into a more manageable condition that people can survive into adulthood.
Nature Outlook

Nature Careers