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| Open AccessInduction of lysosomal exocytosis and biogenesis via TRPML1 activation for the treatment of uranium-induced nephrotoxicity
The roles of lysosomes in uranium (U) decorporation and detoxification remain to be elucidated. Here, the authors demonstrate that TRPML1 activation is an attractive therapeutic strategy to induce lysosomal exocytosis and biogenesis for the treatment of U-induced nephrotoxicity.
- Dengqin Zhong
- , Ruiyun Wang
- & Honghong Chen
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Article
| Open AccessSARS-CoV-2 exposure, symptoms and seroprevalence in healthcare workers in Sweden
Healthcare workers may be at higher risk of SARS-CoV-2 infection than the general population. Here, the authors report 19% seroprevalence of SARS-CoV-2 antibodies among 2,149 employees in a Swedish hospital. Seroprevalence was associated with patient contact and higher than the seroprevalence in the community in same time period.
- Ann-Sofie Rudberg
- , Sebastian Havervall
- & Charlotte Thålin