Since Nature Structural and Molecular Biology was started 30 years ago, our understanding of transcription and mRNA processing has been revolutionized through structural and mechanistic studies. Here, we present our personal views of the advances in understanding the production of mature eukaryotic mRNAs over the past decade.
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Acknowledgements
Work in our laboratories is funded by the Medical Research Council, as part of United Kingdom Research and Innovation, MRC file reference numbers MC_U105192715 (L.A.P.) and MC_UP_1201/30 (S.Z.), and the Wellcome Trust, grant 225217/Z/22/Z (L.A.P.).
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Passmore, L.A., Zhang, S. Mechanisms of transcription and RNA processing. Nat Struct Mol Biol 31, 730–731 (2024). https://doi.org/10.1038/s41594-024-01312-8
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DOI: https://doi.org/10.1038/s41594-024-01312-8