By integrating spatially resolved single-cell RNA sequencing (scRNA-seq) and Stereo-seq data, two studies in this issue characterize molecular signatures of liver cell types and their interactions in homeostasis, damage, repair and regeneration.
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References
Xu, J. et al. Nat. Genet. https://doi.org/10.1038/s41588-024-01709-7 (2024).
Wu, B. et al. Nat. Genet. https://doi.org/10.1038/s41588-024-01687-w (2024).
Moses, L. & Pachter, L. Nat. Methods 19, 534–546 (2022).
Ståhl, P. L. et al. Science 353, 78–82 (2016).
Halpern, K. B. et al. Nature 542, 352–356 (2017).
Hildebrandt, F. et al. Nat. Commun. 12, 7046 (2021).
Lotto, J., Stephan, T. L. & Hoodless, P. A. Nat. Rev. Gastroenterol. Hepatol. 20, 561–581 (2023).
Ben-Moshe, S. et al. Nat. Metab. 1, 899–911 (2019).
Rosen, Y. et al. Preprint at bioRxiv https://doi.org/10.1101/2023.11.28.568918 (2023).
Schott, M. et al. Preprint at bioRxiv https://doi.org/10.1101/2023.12.22.572554 (2023).
Ekvall, M. et al. Nat. Methods 21, 673–679 (2024).
Acknowledgements
E.R.A. acknowledges support from Karolinska Institutet Career Ladder (2-195/2021), the Swedish Research Council (2023-01847), the Swedish Foundations' Starting Grant/The Ragnar Söderberg Foundation (S11/20) and the Knut and Alice Wallenberg Foundation (2020,0109). L.B. acknowledges funding from the European Union’s Horizon Europe research and innovation programme under the Marie Skłodowska-Curie grant agreement no. 101057846.
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Belicova, L., Van Hul, N. & Andersson, E.R. Understanding liver repair through space and time. Nat Genet 56, 740–742 (2024). https://doi.org/10.1038/s41588-024-01741-7
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DOI: https://doi.org/10.1038/s41588-024-01741-7