Multidimensional and single-cell profiling of peripheral blood and inflamed tissues is a powerful and high-resolution tool for the stratification of patients with autoimmune rheumatic diseases into distinct cellular and/or molecular endotypes. The road towards precision rheumatology is long, but the time has come to enter the territory of clinical validation.
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G.D.K. is a full-time employee and shareholder at Regeneron Pharmaceuticals. A.G.P. declares no competing interests.
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Kalliolias, G.D., Papavassiliou, A.G. Advancing precision rheumatology through tissue and blood profiling. Nat Rev Rheumatol (2024). https://doi.org/10.1038/s41584-024-01115-7
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DOI: https://doi.org/10.1038/s41584-024-01115-7