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Nature Medicine 14, 379-381 (1 April 2008) | doi:10.1038/nm1732;

Therapeutic cloning in individual parkinsonian mice

Viviane Tabar , Mark Tomishima , Georgia Panagiotakos , Sayaka Wakayama , Jayanthi Menon , Bill Chan , Eiji Mizutani , George Al-Shamy , Hiroshi Ohta , Teruhiko Wakayama & Lorenz Studer

Cell transplantation with embryonic stem (ES) cell progeny requires immunological compatibility with host tissue. 'Therapeutic cloning' is a strategy to overcome this limitation by generating nuclear transfer (nt)ES cells that are genetically matched to an individual.

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