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Nature Medicine 13, 1496-1503 (1 December 2007) | doi:10.1038/nm1672;
PPAR-|[gamma]| regulates osteoclastogenesis in mice
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Abstract
Osteoclasts are bone-resorbing cells derived from hematopoietic precursors of the monocyte-macrophage lineage. Regulation of osteoclast function is central to the understanding of bone diseases such as osteoporosis, rheumatoid arthritis and osteopetrosis.
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