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Nature Medicine 10, 982-986 (1 September 2004) | doi:10.1038/nm1098;
CalDAG-GEFI integrates signaling for platelet aggregation and thrombus formation
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Abstract
Signaling through the second messengers calcium and diacylglycerol (DAG) is a critical element in many biological systems. Integration of calcium and DAG signals has been suggested to occur primarily through protein kinase C family members, which bind both calcium and DAG.
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