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Nature Medicine 12, 882-884 (1 August 2006) | doi:10.1038/nm0806-882;

Embryogenesis meets tumorigenesis

John T Lee & Meenhard Herlyn

Metastatic melanoma remains one of the deadliest diseases, with a 5-year survival rate of less than 20%. The identification of new biological mediators of disease is the most rational approach to developing drugs to shift these dismal odds.

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