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Nature Medicine 13, 678-679 (1 June 2007) | doi:10.1038/nm0607-678;
Research highlights
Abstract
Protecting the heart from stress The heart responds to increased mechanical stress by enlarging and remodeling; this response is thought to be adaptive, but can ultimately lead to heart failure. Shoji Sanada et al. report that interleukin-33 (IL-33), acting on its receptor ST2, protects the heart from the deleterious effects of mechanical stress (J.
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