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Nature Medicine 13, 667-669 (1 June 2007) | doi:10.1038/nm0607-667;

Heme moves to center stage in cerebral malaria

Nicholas H Hunt & Roland Stocker

When malaria parasites infect host erythrocytes, they feed on hemoglobin, releasing large quantities of free heme. By catalyzing free radical reactions, free heme is poisonous to both parasite and host.

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