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Nature Medicine 12, 511-512 (1 May 2006) | doi:10.1038/nm0506-511;
Overcoming insulin resistance with CNTF
Abstract
The ability to maintain normal blood glucose levels involves a complex interplay between insulin secretion by pancreatic beta cells and responsiveness of organs, in particular liver, adipose tissue and skeletal muscle. Type 2 diabetes is commonly associated with obesity and results from insufficient insulin production and reduced sensitivity to insulin.
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