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Nature Medicine 14, 118-119 (1 February 2008) | doi:10.1038/nm0208-118;
Safer, longer-lasting regulatory T cells with |[beta]|-catenin
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Abstract
The vital role of regulatory T (Treg) cells in maintaining self-tolerance is exquisitely clear. Defects in Treg cell development lead to systemic autoimmunity and early death in both mice and humans.
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