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Nature Medicine 12, 171-172 (1 February 2006) | doi:10.1038/nm0206-171;
Angiogenesis and inflammation face off
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Abstract
A study in this issue brings together angiogenesis and inflammation, two processes long thought to involve few common molecular mechanisms. Fiedler et al. find that a well-known regulator of angiogenesis, angiopoietin-2 (Ang-2) can upregulate inflammatory responses—revealing a common signaling pathway for inflammation and angiogenesis, the growth of new blood vessels.
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