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Published online 18 February 1999 | Nature | doi:10.1038/news990218-1
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Counting the cost of cyclosporine
An increased risk of cancer is one of the most feared side-effects of the powerful immunosuppressant drugs which have immeasurably improved the success of organ and bone marrow transplantation. For a long time the increased cancer rates seen in immunosuppressed patients were believed to be entirely an effect of the damping-down of the immune system, and with it the body’s presumed ability to detect and destroy incipient cancer cells.
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