Practice Point

Nature Clinical Practice Urology (2005) 2, 584-585
doi:10.1038/ncpuro0355  
Received 16 September 2005 | Accepted 20 October 2005

Can we preoperatively identify men who are at high risk for aggressive prostate cancer?

Stephen J Freedland

Correspondence Department of Surgery, Division of Urology, Duke University School of Medicine, Durham, NC 27710, USA

Email
 steve.freedland@duke.edu

This article has no abstract so we have provided the first paragraph of the full text.

"Doc, what are my chances?" As clinicians, we have all heard these words countless times before. Though these words could come from patients with any disease, they are particularly relevant for those with prostate cancer. Among men with prostate cancer, the vast majority will die of other causes.1 Yet prostate cancer remains the number two cause of death from cancer among men. Is it possible to identify, before treatment, those men who are at the highest risk of death from prostate cancer, and, likewise, to identify those men who are at lowest risk? These are not new questions; however, the study by D'Amico and colleagues builds upon existing concepts and begins to help us understand who the highest-risk and lowest-risk patients are.

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