Preoperative radiotherapy for rectal cancer: beyond local control
Abdelkarim S Allal* and Claudio Soravia
Correspondence *Division of Radiation Oncology, Geneva University Hospitals, Rue Micheli-du-Crest, 24, Geneva 1205, Switzerland
Email abdelkarim.allal@hcuge.ch
This article has no abstract so we have provided the first paragraph of the full text.
The main finding reported by Folkesson et al. from the long-term results of the SRCT was that, compared with surgery alone, preoperative short-course radiotherapy (25 Gy over 5 days) has positive effects on overall survival and local control. In line with this finding, a Dutch randomized controlled trial showed that preoperative short-course radiotherapy and total mesorectal excision (TME) is superior to TME alone, at least in terms of local control.1 The question is should we now consider short-course preoperative radiotherapy with TME as the gold standard therapy for nonmetastatic rectal cancer?
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