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Nature Clinical Practice Oncology (2005) 2, 433
doi:10.1038/ncponc0266  

The origins of multifocal papillary thyroid tumors

Christine Kyme

This article has no abstract so we have provided the first paragraph of the full text.

Multifocal papillary thyroid tumors are associated with an increased risk of persistent local disease and regional recurrence after treatment, as well as with lymph-node and distant metastases. A recent study by Shattuck et al. investigated the origins of such multiple distinct thyroid tumor foci, using X-chromosome inactivation.

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