Can abnormal evoked potentials predict future clinical disability in patients with multiple sclerosis?
Frank L Mastaglia
Correspondence Centre for Neuromuscular and Neurological Disorders, 4th Floor, A Block, Queen Elizabeth II Medical Centre, Nedlands, WA 6009, Australia
Email flmast@cyllene.uwa.edu.au
This article has no abstract so we have provided the first paragraph of the full text.
The clinical course of patients with MS is extremely variable, and predicting the likelihood of progression and the eventual degree of disability is difficult in the early stages of the disease. Certain features such as the age at onset, the area of the CNS initially affected (e.g. spinal cord, brainstem, cerebellum) and the frequency of relapses in the first 2 years of the illness can give some guide to the subsequent course of disease.1 The number and volume of brain lesions on MRI have also been shown to be of some prognostic value.2 None of these criteria, however, are sufficiently reliable in their own right to predict what the future holds for an individual patient.
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