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Nature Clinical Practice Nephrology (2007) 3, 120-121
doi:10.1038/ncpneph0422  
Received 22 November 2006 | Accepted 18 December 2006

Continuous dialysis is not superior to intermittent dialysis in acute kidney injury of the critically ill patient

Jonathan Himmelfarb

Correspondence Maine Medical Center, 22 Bramhall Street, Portland, ME 04102, USA

Email
 himmej@mmc.org

The author of this counterpoint argues that the results of recently published randomized clinical trials call into question the assumption that continuous renal replacement therapy is inherently superior to intermittent hemodialysis for patients in the intensive care unit with severe acute kidney injury. The second half of his article examines why this might be. Has intermittent hemodialysis become safer and more efficacious? Might continuous renal replacement therapy be less safe and/or efficacious than previously thought?

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