Practice Point

Nature Clinical Practice Nephrology (2006) 2, 478-479
doi:10.1038/ncpneph0270  
Received 21 April 2006 | Accepted 7 July 2006

Improved short-term outcomes with early use of isovolemic hemofiltration in patients with septic shock

Peter Rogiers

Correspondence Intensive Care Unit, Middelheim General Hospital, Ziekenhuisnetwerk Antwerpen, Antwerp, Belgium

Email
 peter.rogiers@zna.be

This article has no abstract so we have provided the first paragraph of the full text.

Sepsis and septic shock are associated with high morbidity and mortality rates, the latter ranging from 32% to 54%.1 The search for new therapeutic interventions to improve the outcome of septic shock remains challenging. One possible approach is the use of hemofiltration to remove inflammatory substances such as endotoxin, cytokines, oxygen free radicals, and arachidonic acid metabolites. This strategy forms the basis of the retrospective study by Piccinni and colleagues.

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