Practice Point

Nature Clinical Practice Nephrology (2006) 2, 484-485
doi:10.1038/ncpneph0266  
Received 15 March 2006 | Accepted 5 June 2006

Does plasmapheresis desensitize kidney transplant recipients more effectively than high-dose immunoglobulin?

Suphamai Bunnapradist

Correspondence David Geffen School of Medicine, Department of Medicine, Division of Nephrology, Kidney, and Pancreas Transplant Research Office, 924 Westwood Boulevard, Suite 860, Los Angeles, CA 90095-7306, USA

Email
 bunnapradist@mednet.ucla.edu

This article has no abstract so we have provided the first paragraph of the full text.

Sensitization (the presence of preformed antibodies against human leukocyte antigen [HLA] in the blood) is a major barrier to successful kidney transplantation.1 In recent years, many therapeutic approaches have been developed for the reduction or removal of HLA antibodies. Two such 'desensitization' protocols have been used successfully: high-dose IVIG, and plasmapheresis plus low-dose IVIG.2, 3

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