Renal apoA-I amyloidosis is a rare disease that is difficult to recognize

Pippa Murdie

This article has no abstract so we have provided the first paragraph of the full text.

Mutations in apolipoprotein A-I (apoA-I) result in deposition of amyloid fibrils, predominantly in the liver, kidney and heart, and cause a rare, late-onset, autosomal dominant form of amyloidosis. In a paper published in the Journal of the American Society of Nephrology, Gregorini et al. add to their previous data regarding renal involvement in patients with hereditary apoA-I amyloidosis associated with a Leu75Pro heterozygous mutation.

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