Calcineurin-inhibitor-free maintenance immunosuppression
Rachael Williams
This article has no abstract so we have provided the first paragraph of the full text.
Calcineurin inhibitors (CNIs) such as ciclosporin and tacrolimus are nephrotoxic, and contribute to late dysfunction of renal grafts. New results from two randomized controlled trials, published in the American Journal of Transplantation, support a CNI-free maintenance immunosuppression regimen based on the less-toxic drug sirolimus.
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