Review

Nature Clinical Practice Gastroenterology & Hepatology (2004) 1, 46-52
doi:10.1038/ncpgasthep0025  

Mechanisms of Disease: advances in understanding the mechanisms leading to chronic pancreatitis

David C Whitcomb

Correspondence GI Administration, Mezzanine level 2, C-Wing, UPMC Presbyterian, 200 Lothrop Street, Pittsburgh, PA 15213, USA

Email
 whitcomb@pitt.edu

At present there is no cure for chronic pancreatitis—a progressive condition that culminates in the destruction of the pancreas. Recent advances in genetic and immunologic research have spawned new insights into the mechanisms underlying chronic pancreatitis, and new models are helping us understand associated risk factors and etiologies.

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