Treatment of recurrent Clostridium difficile-associated disease
Christina M Surawicz
Correspondence Department of Medicine, University of Washington School of Medicine, Harborview Medical Center, 325 Ninth Avenue, Box 359773, Seattle, WA 98104, USA
Email surawicz@u.washington.edu
At present, there is no uniformly effective treatment for recurrent Clostridium difficile-associated disease. Tapering and pulsing antibiotics after a 10-day standard course can decrease the recurrence of disease, as can adjunct use of the probiotic Saccharomyces boulardii. Restoration of normal colonic flora might be another treatment option, and new treatment approaches being developed include a vaccine.
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