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Nature Clinical Practice Endocrinology & Metabolism (2007) 3, 4-5
doi:10.1038/ncpendmet0355  
Received 2 March 2006 | Accepted 10 July 2006

Severe iatrogenic hypoglycemia in type 2 diabetes mellitus

Philip E Cryer

Correspondence Campus Box 8127, Washington University School of Medicine, 660 South Euclid Avenue, St Louis, MO 63109, USA

Email
 pcryer@wustl.edu

Hypoglycemia-associated autonomic failure (HAAF) describes the syndromes of defective glucose regulation and hypoglycemia unawareness. Originally characterized in type 1 diabetes, the author of this Viewpoint suggests that HAAF is also a component of iatrogenic hypoglycemia in patients with type 2 diabetes, and represents a barrier to glycemic control.

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