Cardiac resynchronization therapy lowers mortality in advanced heart failure
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Cardiac resynchronization therapy (CRT) improves symptoms, quality of life and exercise capacity in patients with advanced heart failure; however, studies to date have been underpowered to assess the effects of CRT on mortality. This meta-analysis by Rivero-Ayerza et al. combines data from 2,371 patients taken from 5 studies that compared the effect on survival of CRT alone versus optimum pharmacologic therapy. The mean age of the study populations included in this meta-analysis ranged from 64 years to 68 years, and the majority of patients were male.
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