Multiple acute ischemic lesion pattern can occur in stroke with no embolic source

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A pattern of multiple acute ischemic lesions on diffusion-weighted MRI (DWI-MRI) is thought to indicate an embolic source of stroke. In some stroke patients with this lesion pattern, however, no embolic source can be detected, and the stroke is described as cryptogenic; in other patients, patent foramen ovale (PFO) is the only pathological finding that might operate as an embolic source. Jauss et al. compared the prevalence of the multiple acute ischemic lesion pattern in patients with cryptogenic stroke with that in patients with PFO.

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