Apolipoprotein A-I mimetic peptides and their role in atherosclerosis prevention
Mohamad Navab*, GM Anantharamaiah, Srinivasa T Reddy and Alan M Fogelman
Correspondence *Division of Cardiology, David Geffen School of Medicine at UCLA, BH-307CHS, 10833 Le Conte Avenue, Los Angeles, CA 90095, USA
Email mnavab@mednet.ucla.edu
Although apolipoprotein A-I has benefits in relation to atherosclerosis, this large protein can only be administered intravenously and is difficult and expensive to manufacture. Smaller peptides that mimic apolipoprotein A-I and yield the same beneficial effects have, therefore, been sought. The advances being made in this therapeutic area are described.
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