Disease mechanisms and emerging therapies: protein kinases and their inhibitors in myocardial disease
Mark E Anderson*, Linda S Higgins and Howard Schulman
Correspondence *Cardiovascular Research Center, University of Iowa, 200 Hawkins Drive, Room E315 GH, Iowa City, IA 52242–1081, USA
Email mark-e-anderson@uiowa.edu
Many protein kinases are positioned proximal to critical proteins that mediate cell function. Since these functions can be altered by disease, attention has turned to protein kinases as therapeutic targets. In this Review, the role of protein kinases in myocardial disease, and the pharmacologic therapy possibilities they present are discussed.
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