Review

Nature Clinical Practice Cardiovascular Medicine (2006) 3, 368-376
doi:10.1038/ncpcardio0584  
Received 2 December 2005 | Accepted 30 March 2006

Diastolic ventricular interaction: from physiology to clinical practice

Lynne Williams* and Michael Frenneaux

Correspondence *Department of Cardiovascular Medicine, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK

Email
 l.k.williams@bham.ac.uk

Since the ventricles share a common septum, interaction between them is inevitable. Performance of each ventricle is influenced by the compliance, filling volume and pressure of the other, as well as by external constraints from the pericardium. In this review, the role of direct diastolic ventricular interaction is explored in various cardiovascular disorders.

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