Detection of high-risk atherosclerotic plaques by palpography
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Acute coronary events frequently result from atherosclerotic plaque rupture at apparently noncritical sites. Although pathologic examination shows that specific plaque characteristics correlate with fatal ischemic events, plaques at high risk of rupture cannot be identified by conventional imaging techniques. Van Mieghem et al. assessed noninvasive identification of atherosclerotic plaques by multislice CT angiography compared with intravascular ultrasound (IVUS), the current gold standard technique. They then assessed the ability of two IVUS-based techniques—palpography and plaque ultrasonography—to identify high-risk atherosclerotic plaques in patients referred for percutaneous coronary intervention.
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