Research Highlights

Nature Clinical Practice Cardiovascular Medicine (2006) 3, 295-296
doi:10.1038/ncpcardio0551  

Cangrelor inhibits platelet activation in patients undergoing PCI

Jim Casey

This article has no abstract so we have provided the first paragraph of the full text.

Complications during percutaneous cardiac intervention (PCI) can be caused by platelet-initiated acute thrombosis and coronary embolization. The P2Y12-receptor antagonist cangrelor has been found to inhibit platelet activation. In a two-part study involving a total of 399 patients undergoing PCI, Greenbaum et al. assessed the safety and pharmacodynamics of cangrelor and compared this drug first with placebo and then with abciximab.

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