Mixed results after autologous stem-cell transplantation for STEMI
Kate Matthews
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Despite the benefit of reperfusion therapies, ST-segment elevation myocardial infarction (STEMI) is associated with a loss of viable myocardium and left ventricular (LV) function. Intracoronary transfer of autologous stem cells from bone marrow might improve LV remodeling and function following STEMI, but trials investigating this procedure have not included appropriate placebo control groups. Janssens and coauthors compared the effects of intracoronary stem-cell transfer with those of placebo transfer.
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