Research Highlights

Nature Clinical Practice Cardiovascular Medicine (2006) 3, 60
doi:10.1038/ncpcardio0423  

Closure of interatrial communications is effective in patients with right-to-left shunt

Pippa Murdie

This article has no abstract so we have provided the first paragraph of the full text.

Right-to-left shunt through an interatrial communication occurs when pressure in the right atrium is higher than that in the left; it can result in systemic embolism and systemic desaturation. It occurs in conditions such as pulmonary hypertension and right ventricular dysfunction, and can increase risk of stroke and limit ability to carry out physical exercise. The standard treatment in adults is closure of interatrial communications. Agnoletti et al. studied the effectiveness of this procedure in young patients who had undergone biventricular repair for congenital heart disease.

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