The impact of progenitor cells in atherosclerosis
Qingbo Xu
Correspondence Department of Cardiac and Vascular Sciences, St George's, University of London, Cranmer Terrace, London SW17 0RE, UK
Email q.xu@sghms.ac.uk
The integrity of the endothelium can be damaged in various ways, making the formation of atherosclerotic lesions possible. The source of cells involved in endothelial repair and smooth-muscle accumulation in lesions has been debated, but data suggest progenitor cells as a likely origin. Their role in the pathogenesis of atherosclerosis is discussed here.
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