Review

Nature Clinical Practice Cardiovascular Medicine (2005) 2, 415-422
doi:10.1038/ncpcardio0271  
Received 18 February 2004 | Accepted 31 May 2005

Drug Insight: an overview of current anticoagulation therapy after heart valve replacement

Detlef Hering*, Cornelia Piper and Dieter Horstkotte

Correspondence *Department of Cardiology, Heart Center North Rhine-Westphalia, Ruhr University Bochum, Georgstrasse 11, 32545, Bad Oeynhausen, Germany

Email
 akohlstaedt@hdz-nrw.de

Patients who receive most types of modern prosthetic heart valve are currently also given long-term, low-intensity anticoagulation therapy to reduce the risk of thromboembolic complications. In this review, the authors discuss the current recommendations for anticoagulation therapy and the data on which these recommendations are based.

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