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Nature Clinical Practice Cardiovascular Medicine (2005) 2, 282-283
doi:10.1038/ncpcardio0219  
Received 1 March 2005 | Accepted 18 April 2005

Fractional flow reserve: can it predict adverse events accurately after coronary stenting?

Steven AJ Chamuleau

Correspondence Academic Medical Center Amsterdam, Department of Cardiology, B2 PO box 22660, 1100 DD Amsterdam, The Netherlands

Email
 s.a.chamuleau@amc.uva.nl

This article has no abstract so we have provided the first paragraph of the full text.

Klauss et al. studied patients undergoing percutaneous coronary intervention (PCI) and stent implantation, of whom 75% were also included in the FFR registry.1 The results confirm those of the registry: FFR after stenting is a strong and independent predictor of MACE. Of 18 cardiac events that occurred, 15 (83%) were target-lesion revascularizations. It is not clear from the data if these revascularizations were preceded by objective evidence of myocardial ischemia. As operators were not blinded to the initial FFR result, bias with respect to the decision of target-lesion revascularization could be a confounding factor.

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