Practice Point

Nature Clinical Practice Cardiovascular Medicine (2005) 2, 286-287
doi:10.1038/ncpcardio0215  
Received 21 February 2005 | Accepted 7 April 2005

Can bedside testing of B-type natriuretic peptide be used to diagnose left-ventricular diastolic dysfunction?

Torbjørn Omland

Correspondence Cardiology Division, Akershus University Hospital, 1478 Lørenskog, Norway

Email
 torbjorn.omland@medisin.uio.no

This article has no abstract so we have provided the first paragraph of the full text.

Arterial hypertension and coronary artery disease are common causes of HF, but HF is often preceded by a phase of asymptomatic systolic or diastolic dysfunction. Echocardiography can be used in patients with HF to determine whether left-ventricular systolic or diastolic function is impaired, but can also be performed to show such dysfunction in asymptomatic individuals. Reduced left-ventricular ejection fraction is a widely accepted criterion for systolic dysfunction, but multiple echocardiographic indices of left-ventricular relaxation, filling, diastolic distensibility and stiffness have been proposed as diagnostic criteria for diastolic dysfunction. Even though diastolic HF is common and can be managed differently from systolic HF, a standardized assessment of left-ventricular diastolic function has yet to be integrated into routine clinical practice in echocardiography laboratories.

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