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Nature Clinical Practice Cardiovascular Medicine (2005) 2, 238-239
doi:10.1038/ncpcardio0188  
Received 4 February 2005 | Accepted 2 March 2005

Can the measurement of impaired flow-mediated dilation predict in-stent restenosis?

Matthew I Worthley, Francois Charbonneau and Todd J Anderson*

Correspondence *Department of Cardiovascular Sciences and the Libin Cardiovascular Institute of Alberta, Faculty of Medicine, University of Calgary, Health Sciences Centre, 3330 University Drive NW, Calgary, Alberta T2N 4N1 Canada

Email
 Todd.Anderson@CalgaryHealthRegion.ca

This article has no abstract so we have provided the first paragraph of the full text.

For many years the endothelium was thought of as merely an inert physical barrier between the blood and vessel wall. Over the last 25 years, however, our understanding of the functional significance of this single-cell lining has increased exponentially. The endothelium protects the vessel wall predominantly through production of nitric oxide. Dysfunction of the endothelium increases the incidence of adverse cardiovascular outcomes.1

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