Risks and benefits of warfarin plus aspirin
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There is a lack of consensus on whether patients starting warfarin therapy should continue taking daily aspirin. Although antithrombotic protection is likely to be superior when both agents are used, some clinicians fear that the risk of increased bleeding is unacceptably high. In an attempt to resolve this problem, Larson and Fisher have carried out a systematic review and meta-analysis of nine randomized trials comparing warfarin plus aspirin versus warfarin alone.
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