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Neurodegeneration

Taming tangled tau

Nature volume 547, pages 170–171 (2017)Cite this article

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The protein tau forms abnormal filamentous aggregates called tangles in the brains of people with neurodegeneration. Structures of two such filaments offer pathways to a deeper understanding of Alzheimer's disease. See Article p.185

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Figure 1: Structures of tau protein filaments.

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Authors and Affiliations

  1. and in the Departments of Biological Chemistry and Chemistry & Biochemistry, Howard Hughes Medical Institute and the UCLA-DOE Institute, University of California Los Angeles, Los Angeles, 90095-1570, USA

    David S. Eisenberg & Michael R. Sawaya

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  1. David S. Eisenberg
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  2. Michael R. Sawaya
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Correspondence to David S. Eisenberg or Michael R. Sawaya.

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D.S.E. declares competing financial interests. See go.nature.com/2sxbcx1 for details.

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Eisenberg, D., Sawaya, M. Taming tangled tau. Nature 547, 170–171 (2017). https://doi.org/10.1038/nature23094

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