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Neurobiology

New player in pain

Long-term pain must be accompanied by long-term alterations in neuronal signalling — but what causes the changes? In rats, immune-like spinal cells are implicated, together with a molecule new to the field of pain.

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Figure 1: Pain and its pathways.

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McCleskey, E. New player in pain. Nature 424, 729–730 (2003). https://doi.org/10.1038/424729a

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