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Nature 417, 894-896 (27 June 2002) | doi:10.1038/417894a

Proteomics: The society of proteins

Alison Abbott1

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Having realized that proteins usually do their jobs by combining to form transient complexes, biologists are queuing up to study these structures using a powerful electron-microscopy technique. Alison Abbott reports.

Giulio Superti-Furga likes to call himself a protein sociologist. His team has provided powerful evidence for an emerging biological concept: that proteins generally don't work alone, but instead assemble into complexes until their job is done.