The Pharmacogenomics Journal http://www.nature.com/tpj/journal/vaop/ncurrent/rss.rdf Nature Publishing Group en Copyright © Nature Publishing Group The Pharmacogenomics Journal 1470-269X Copyright © Nature Publishing Group permissions@nature.com The Pharmacogenomics Journal http://www.nature.com/aj/images/logos_b_o_w/tpj.gif http://www.nature.com/tpj/ Global variation in CYP2C8–CYP2C9 functional haplotypes http://dx.doi.org/10.1038/tpj.2009.10 Global variation in CYP2C8–CYP2C9 functional haplotypes

The Pharmacogenomics Journal advance online publication, April 21, 2009. doi:10.1038/tpj.2009.10

Authors: William C Speed, Soonmo Peter Kang, David P Tuck, Lyndsay N Harris & Kenneth K Kidd

]]> Global variation in CYP2C8–CYP2C9 functional haplotypes William C Speed Soonmo Peter Kang David P Tuck Lyndsay N Harris Kenneth K Kidd doi:10.1038/tpj.2009.10 The Pharmacogenomics Journal advance online publication, April 21, 2009 2009-04-21 The Pharmacogenomics Journal April 21, 2009 aop current A novel CYP2A6 allele (CYP2A6*35) resulting in an amino-acid substitution (Asn438Tyr) is associated with lower CYP2A6 activity in vivo http://dx.doi.org/10.1038/tpj.2009.11 A novel CYP2A6 allele (CYP2A6*35) resulting in an amino-acid substitution (Asn438Tyr) is associated with lower CYP2A6 activity in vivo

The Pharmacogenomics Journal advance online publication, April 14, 2009. doi:10.1038/tpj.2009.11

Authors: Nael Al Koudsi, Jasjit S Ahluwalia, Shih-Ku Lin, Edward M Sellers & Rachel F Tyndale

]]> A novel CYP2A6 allele (CYP2A6*35) resulting in an amino-acid substitution (Asn438Tyr) is associated with lower CYP2A6 activity in vivo Nael Al Koudsi Jasjit S Ahluwalia Shih-Ku Lin Edward M Sellers Rachel F Tyndale doi:10.1038/tpj.2009.11 The Pharmacogenomics Journal advance online publication, April 14, 2009 2009-04-14 The Pharmacogenomics Journal April 14, 2009 aop current Genetic predictors of response to antidepressants in the GENDEP project http://dx.doi.org/10.1038/tpj.2009.12 Genetic predictors of response to antidepressants in the GENDEP project

The Pharmacogenomics Journal advance online publication, April 14, 2009. doi:10.1038/tpj.2009.12

Authors: Rudolf Uher, Patricia Huezo-Diaz, Nader Perroud, Rebecca Smith, Marcella Rietschel, Ole Mors, Joanna Hauser, Wolfgang Maier, Dejan Kozel, Neven Henigsberg, Mara Barreto, Anna Placentino, Mojca Zvezdana Dernovsek, Thomas G Schulze, Petra Kalember, Astrid Zobel, Piotr M Czerski, Erik Roj Larsen, Daniel Souery, Caterina Giovannini, Joanna M Gray, Cathryn M Lewis, Anne Farmer, Katherine J Aitchison, Peter McGuffin & Ian Craig

]]> Genetic predictors of response to antidepressants in the GENDEP project Rudolf Uher Patricia Huezo-Diaz Nader Perroud Rebecca Smith Marcella Rietschel Ole Mors Joanna Hauser Wolfgang Maier Dejan Kozel Neven Henigsberg Mara Barreto Anna Placentino Mojca Zvezdana Dernovsek Thomas G Schulze Petra Kalember Astrid Zobel Piotr M Czerski Erik Roj Larsen Daniel Souery Caterina Giovannini Joanna M Gray Cathryn M Lewis Anne Farmer Katherine J Aitchison Peter McGuffin Ian Craig doi:10.1038/tpj.2009.12 The Pharmacogenomics Journal advance online publication, April 14, 2009 2009-04-14 The Pharmacogenomics Journal April 14, 2009 aop current A genetic polymorphism of matrix metalloproteinase 9 (MMP-9) affects the changes in circulating MMP-9 levels induced by highly active antiretroviral therapy in HIV patients http://dx.doi.org/10.1038/tpj.2009.13 A genetic polymorphism of matrix metalloproteinase 9 (MMP-9) affects the changes in circulating MMP-9 levels induced by highly active antiretroviral therapy in HIV patients

The Pharmacogenomics Journal advance online publication, April 21, 2009. doi:10.1038/tpj.2009.13

Authors: C Demacq, V B Vasconcellos, A M Marcaccini, R F Gerlach, A A Machado & J E Tanus-Santos

]]> A genetic polymorphism of matrix metalloproteinase 9 (MMP-9) affects the changes in circulating MMP-9 levels induced by highly active antiretroviral therapy in HIV patients C Demacq V B Vasconcellos A M Marcaccini R F Gerlach A A Machado J E Tanus-Santos doi:10.1038/tpj.2009.13 The Pharmacogenomics Journal advance online publication, April 21, 2009 2009-04-21 The Pharmacogenomics Journal April 21, 2009 aop current Cytochrome P450 2D6 activity predicts discontinuation of tamoxifen therapy in breast cancer patients http://dx.doi.org/10.1038/tpj.2009.14 Cytochrome P450 2D6 activity predicts discontinuation of tamoxifen therapy in breast cancer patients

The Pharmacogenomics Journal advance online publication, May 5, 2009. doi:10.1038/tpj.2009.14

Authors: J M Rae, M J Sikora, N L Henry, L Li, S Kim, S Oesterreich, T C Skaar, A T Nguyen, Z Desta, A M Storniolo, D A Flockhart, D F Hayes & V Stearns

]]> Cytochrome P450 2D6 activity predicts discontinuation of tamoxifen therapy in breast cancer patients J M Rae M J Sikora N L Henry L Li S Kim S Oesterreich T C Skaar A T Nguyen Z Desta A M Storniolo D A Flockhart D F Hayes V Stearns doi:10.1038/tpj.2009.14 The Pharmacogenomics Journal advance online publication, May 5, 2009 2009-05-05 The Pharmacogenomics Journal May 5, 2009 aop current Genetic variation in the organic cation transporter 1 is associated with metformin response in patients with diabetes mellitus http://dx.doi.org/10.1038/tpj.2009.15 Genetic variation in the organic cation transporter 1 is associated with metformin response in patients with diabetes mellitus

The Pharmacogenomics Journal advance online publication, April 21, 2009. doi:10.1038/tpj.2009.15

Authors: M L Becker, L E Visser, R H N van Schaik, A Hofman, A G Uitterlinden & B H C Stricker

]]> Genetic variation in the organic cation transporter 1 is associated with metformin response in patients with diabetes mellitus M L Becker L E Visser R H N van Schaik A Hofman A G Uitterlinden B H C Stricker doi:10.1038/tpj.2009.15 The Pharmacogenomics Journal advance online publication, April 21, 2009 2009-04-21 The Pharmacogenomics Journal April 21, 2009 aop current Prevalence of CYP2C9 polymorphisms in the south of Europe http://dx.doi.org/10.1038/tpj.2009.16 Prevalence of CYP2C9 polymorphisms in the south of Europe

The Pharmacogenomics Journal advance online publication, April 21, 2009. doi:10.1038/tpj.2009.16

Authors: Paula Sánchez-Diz, Ana Estany-Gestal, Carmelo Aguirre, Adoración Blanco, Angel Carracedo, Luisa Ibáñez, Marianna Passiu, Lisa Provezza, Ricardo Ramos-Ruiz, Borja Ruiz, Inés Salado-Valdivieso, Eladio A Velasco & Adolfo Figueiras

]]> Prevalence of CYP2C9 polymorphisms in the south of Europe Paula Sánchez-Diz Ana Estany-Gestal Carmelo Aguirre Adoración Blanco Angel Carracedo Luisa Ibáñez Marianna Passiu Lisa Provezza Ricardo Ramos-Ruiz Borja Ruiz Inés Salado-Valdivieso Eladio A Velasco Adolfo Figueiras doi:10.1038/tpj.2009.16 The Pharmacogenomics Journal advance online publication, April 21, 2009 2009-04-21 The Pharmacogenomics Journal April 21, 2009 aop current Olanzapine-induced weight gain is associated with the −759C/T and −697G/C polymorphisms of the HTR2C gene http://dx.doi.org/10.1038/tpj.2009.18 Olanzapine-induced weight gain is associated with the −759C/T and −697G/C polymorphisms of the HTR2C gene

The Pharmacogenomics Journal advance online publication, May 12, 2009. doi:10.1038/tpj.2009.18

Authors: B R Godlewska, L Olajossy-Hilkesberger, M Ciwoniuk, M Olajossy, H Marmurowska-Michałowska, J Limon & J Landowski

]]> Olanzapine-induced weight gain is associated with the −759C/T and −697G/C polymorphisms of the HTR2C gene B R Godlewska L Olajossy-Hilkesberger M Ciwoniuk M Olajossy H Marmurowska-Michałowska J Limon J Landowski doi:10.1038/tpj.2009.18 The Pharmacogenomics Journal advance online publication, May 12, 2009 2009-05-12 The Pharmacogenomics Journal May 12, 2009 aop current Common variations in ERCC2 are associated with response to cisplatin chemotherapy and clinical outcome in osteosarcoma patients http://dx.doi.org/10.1038/tpj.2009.19 Common variations in ERCC2 are associated with response to cisplatin chemotherapy and clinical outcome in osteosarcoma patients

The Pharmacogenomics Journal advance online publication, May 12, 2009. doi:10.1038/tpj.2009.19

Authors: D Caronia, A Patiño-García, R L Milne, M Zalacain-Díez, G Pita, M R Alonso, L T Moreno, L Sierrasesumaga-Ariznabarreta, J Benítez & A González-Neira

]]> Common variations in ERCC2 are associated with response to cisplatin chemotherapy and clinical outcome in osteosarcoma patients D Caronia A Patiño-García R L Milne M Zalacain-Díez G Pita M R Alonso L T Moreno L Sierrasesumaga-Ariznabarreta J Benítez A González-Neira doi:10.1038/tpj.2009.19 The Pharmacogenomics Journal advance online publication, May 12, 2009 2009-05-12 The Pharmacogenomics Journal May 12, 2009 aop current Combined analysis of EGF+61G>A and TGFB1+869T>C functional polymorphisms in the time to androgen independence and prostate cancer susceptibility http://dx.doi.org/10.1038/tpj.2009.20 Combined analysis of EGF+61G>A and TGFB1+869T>C functional polymorphisms in the time to androgen independence and prostate cancer susceptibility

The Pharmacogenomics Journal advance online publication, June 2, 2009. doi:10.1038/tpj.2009.20

Authors: A L Teixeira, R Ribeiro, A Morais, F Lobo, A Fraga, F Pina, F M Calais-da-Silva, F E Calais-da-Silva & R Medeiros

]]> Combined analysis of EGF+61G>A and TGFB1+869T>C functional polymorphisms in the time to androgen independence and prostate cancer susceptibility A L Teixeira R Ribeiro A Morais F Lobo A Fraga F Pina F M Calais-da-Silva F E Calais-da-Silva R Medeiros doi:10.1038/tpj.2009.20 The Pharmacogenomics Journal advance online publication, June 2, 2009 2009-06-02 The Pharmacogenomics Journal June 2, 2009 aop current Association of genotypes of the CYP3A cluster with midazolam disposition in vivo http://dx.doi.org/10.1038/tpj.2009.21 Association of genotypes of the CYP3A cluster with midazolam disposition in vivo

The Pharmacogenomics Journal advance online publication, June 9, 2009. doi:10.1038/tpj.2009.21

Authors: J Miao, Y Jin, R L Marunde, S Kim, S Quinney, M Radovich, L Li & S D Hall

]]> Association of genotypes of the CYP3A cluster with midazolam disposition in vivo J Miao Y Jin R L Marunde S Kim S Quinney M Radovich L Li S D Hall doi:10.1038/tpj.2009.21 The Pharmacogenomics Journal advance online publication, June 9, 2009 2009-06-09 The Pharmacogenomics Journal June 9, 2009 aop current Corticosteroid effects on blood gene expression in Duchenne muscular dystrophy http://dx.doi.org/10.1038/tpj.2009.22 Corticosteroid effects on blood gene expression in Duchenne muscular dystrophy

The Pharmacogenomics Journal advance online publication, June 2, 2009. doi:10.1038/tpj.2009.22

Authors: L Lit, F R Sharp, M Apperson, D Z Liu, W L Walker, I Liao, H Xu, B P Ander & B Wong

]]> Corticosteroid effects on blood gene expression in Duchenne muscular dystrophy L Lit F R Sharp M Apperson D Z Liu W L Walker I Liao H Xu B P Ander B Wong doi:10.1038/tpj.2009.22 The Pharmacogenomics Journal advance online publication, June 2, 2009 2009-06-02 The Pharmacogenomics Journal June 2, 2009 aop current Intermediate metabolizer: increased side effects in psychoactive drug therapy. The key to cost-effectiveness of pretreatment CYP2D6 screening? http://dx.doi.org/10.1038/tpj.2009.23 Intermediate metabolizer: increased side effects in psychoactive drug therapy. The key to cost-effectiveness of pretreatment CYP2D6 screening?

The Pharmacogenomics Journal advance online publication, May 19, 2009. doi:10.1038/tpj.2009.23

Authors: B Laika, S Leucht, S Heres & W Steimer

]]> Intermediate metabolizer: increased side effects in psychoactive drug therapy. The key to cost-effectiveness of pretreatment CYP2D6 screening? B Laika S Leucht S Heres W Steimer doi:10.1038/tpj.2009.23 The Pharmacogenomics Journal advance online publication, May 19, 2009 2009-05-19 The Pharmacogenomics Journal May 19, 2009 aop current Candidate-gene association analysis of response to risperidone in African-American and white patients with schizophrenia http://dx.doi.org/10.1038/tpj.2009.24 Candidate-gene association analysis of response to risperidone in African-American and white patients with schizophrenia

The Pharmacogenomics Journal advance online publication, May 19, 2009. doi:10.1038/tpj.2009.24

Authors: B A Fijal, B J Kinon, S Kapur, V L Stauffer, R R Conley, H H Jamal, J M Kane, M M Witte & J P Houston

]]> Candidate-gene association analysis of response to risperidone in African-American and white patients with schizophrenia B A Fijal B J Kinon S Kapur V L Stauffer R R Conley H H Jamal J M Kane M M Witte J P Houston doi:10.1038/tpj.2009.24 The Pharmacogenomics Journal advance online publication, May 19, 2009 2009-05-19 The Pharmacogenomics Journal May 19, 2009 aop current APOE gene polymorphisms and response to statin therapy http://dx.doi.org/10.1038/tpj.2009.25 APOE gene polymorphisms and response to statin therapy

The Pharmacogenomics Journal advance online publication, June 16, 2009. doi:10.1038/tpj.2009.25

Authors: E Zintzaras, G D Kitsios, F Triposkiadis, J Lau & G Raman

]]> APOE gene polymorphisms and response to statin therapy E Zintzaras G D Kitsios F Triposkiadis J Lau G Raman doi:10.1038/tpj.2009.25 The Pharmacogenomics Journal advance online publication, June 16, 2009 2009-06-16 The Pharmacogenomics Journal June 16, 2009 aop current A common variant in DRD3 gene is associated with risperidone-induced extrapyramidal symptoms http://dx.doi.org/10.1038/tpj.2009.26 A common variant in DRD3 gene is associated with risperidone-induced extrapyramidal symptoms

The Pharmacogenomics Journal advance online publication, June 9, 2009. doi:10.1038/tpj.2009.26

Authors: P Gassó, S Mas, M Bernardo, S Álvarez, E Parellada & A Lafuente

]]> A common variant in DRD3 gene is associated with risperidone-induced extrapyramidal symptoms P Gassó S Mas M Bernardo S Álvarez E Parellada A Lafuente doi:10.1038/tpj.2009.26 The Pharmacogenomics Journal advance online publication, June 9, 2009 2009-06-09 The Pharmacogenomics Journal June 9, 2009 aop current Alterations of gene expression in blood cells associated with chronic fatigue in breast cancer survivors http://dx.doi.org/10.1038/tpj.2009.27 Alterations of gene expression in blood cells associated with chronic fatigue in breast cancer survivors

The Pharmacogenomics Journal advance online publication, June 23, 2009. doi:10.1038/tpj.2009.27

Authors: H Landmark-Høyvik, K V Reinertsen, J H Loge, S D Fosså, A L Børresen-Dale & V Dumeaux

]]> Alterations of gene expression in blood cells associated with chronic fatigue in breast cancer survivors H Landmark-Høyvik K V Reinertsen J H Loge S D Fosså A L Børresen-Dale V Dumeaux doi:10.1038/tpj.2009.27 The Pharmacogenomics Journal advance online publication, June 23, 2009 2009-06-23 The Pharmacogenomics Journal June 23, 2009 aop current Influence of ethnicity on pharmacogenetic variation in the Ghanaian population http://dx.doi.org/10.1038/tpj.2009.28 Influence of ethnicity on pharmacogenetic variation in the Ghanaian population

The Pharmacogenomics Journal advance online publication, June 23, 2009. doi:10.1038/tpj.2009.28

Authors: J L Yen-Revollo, D J Van Booven, E J Peters, J M Hoskins, R M Engen, H D Kannall, D Ofori-Adjei, H L McLeod & S Marsh

]]> Influence of ethnicity on pharmacogenetic variation in the Ghanaian population J L Yen-Revollo D J Van Booven E J Peters J M Hoskins R M Engen H D Kannall D Ofori-Adjei H L McLeod S Marsh doi:10.1038/tpj.2009.28 The Pharmacogenomics Journal advance online publication, June 23, 2009 2009-06-23 The Pharmacogenomics Journal June 23, 2009 aop current Association of nicotinic acetylcholine receptor subunit α4 polymorphisms with nicotine dependence in 5500 Germans http://dx.doi.org/10.1038/tpj.2009.6 Association of nicotinic acetylcholine receptor subunit α4 polymorphisms with nicotine dependence in 5500 Germans

The Pharmacogenomics Journal advance online publication, March 17, 2009. doi:10.1038/tpj.2009.6

Authors: L P Breitling, N Dahmen, K Mittelstraß, D Rujescu, J Gallinat, C Fehr, I Giegling, C Lamina, T Illig, H Müller, E Raum, D Rothenbacher, H-E Wichmann, H Brenner & G Winterer

]]> Association of nicotinic acetylcholine receptor subunit α4 polymorphisms with nicotine dependence in 5500 Germans L P Breitling N Dahmen K Mittelstraß D Rujescu J Gallinat C Fehr I Giegling C Lamina T Illig H Müller E Raum D Rothenbacher H-E Wichmann H Brenner G Winterer doi:10.1038/tpj.2009.6 The Pharmacogenomics Journal advance online publication, March 17, 2009 2009-03-17 The Pharmacogenomics Journal March 17, 2009 aop current